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Stroke

HNF1A · rs55931441

Where this position leads

Condition: Ischaemic Stroke

rs55931441 Condition: Ischaemic Stroke Ischaemic Stroke Condition rs55931441 rs55931441 HNF1A

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Stroke compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Stroke.
G/G Published research associates this genotype with typical/baseline likelihood of Stroke — no copies of the reported risk allele.
Source
Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke
Keene KL, Hyacinth HI, Bis JC, Kittner SJ, Mitchell BD, Cheng YC, Pare G, Chong M, O'Donnell M, Meschia JF, Chen WM, Sale MM
and 35 more — show all
Rich SS, Nalls MA, Zonderman AB, Evans MK, Wilson JG, Correa A, Markus HS, Traylor M, Lewis CM, Carty CL, Reiner A, Haessler J, Langefeld CD, Gottesman R, Mosley TH, Woo D, Yaffe K, Liu Y, Longstreth WT, Psaty BM, Kooperberg C, Lange LA, Sacco R, Rundek T, Lee JM, Cruchaga C, Furie KL, Arnett DK, Benavente OR, Grewal RP, Peddareddygari LR, Dichgans M, Malik R, Worrall BB, Fornage M
COMPASS, SiGN, and METASTROKE Consortia
Stroke · 2020 · PMID 32693751

Questions about rs55931441

What is rs55931441?

rs55931441 is a single position in the genome, in or near the HNF1A gene. Published research associates it with stroke. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs55931441 linked to?

On MyGeneLog this position is linked to Ischaemic Stroke. The research behind each link, and its sources, are set out on that condition page.

Does having rs55931441 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55931441 come from?

GWAS Catalog, Stroke 2020, PMID:32693751. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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