Alzheimer's disease, proxy Alzheimer's disease or related dementias
USP50 · rs55928286
0 201322210Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others10Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 128,681 European ancestry cases, 849,833 European ancestry controls.
The effect
Each copy of the T allele carried 1.05 times the odds of Alzheimer's disease, proxy Alzheimer's disease or related dementias (95% confidence interval 1.03-1.07); p = 5 × 10−9.
How common The T allele had a frequency of about 17% in the people studied.
Where it sits Chromosome 15, band 15q21.2 — in the 3′ untranslated region of USP50.
What each result means
G/GNo copy of the version the research linked to Alzheimer's disease, proxy Alzheimer's disease or related dementias. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Alzheimer's disease, proxy Alzheimer's disease or related dementias. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Alzheimer's disease, proxy Alzheimer's disease or related dementias. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2026 · PMID 42237039 · open access
Questions about rs55928286
What is rs55928286?
rs55928286 is a single position in the genome, in or near the USP50 gene. Published research associates it with alzheimer's disease, proxy alzheimer's disease or related dementias. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs55928286 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs55928286 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs55928286 come from?
GWAS Catalog, Nature genetics 2026, PMID:42237039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 201322210Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others10Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Alzheimer's disease, proxy Alzheimer's disease or related dementias (rs55928286). MyGeneLog™. https://www.mygenelog.com/variants/rs55928286