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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 225,112 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals; replicated in 445,360 individuals.
The effect
Each copy of the A allele shifted the measure 4.52 mmHg higher (95% confidence interval 3.12-5.93); p = 3 × 10−10.
How common The A allele had a frequency of about 0% in the people studied.
Where it sits Chromosome 8, band 8q24.21 — between genes, 5.4 kb from MTRF1LP2.
What each result means
A/ATwo copies of the version the research linked to Pulse pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Pulse pressure. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Pulse pressure. This is the starting point the study compared everyone against.
Nature genetics · 2019 · PMID 30578418 · open access
Questions about rs559128832
What is rs559128832?
rs559128832 is a single position in the genome, in or near the near MTRF1LP2 gene. Published research associates it with pulse pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs559128832 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs559128832 come from?
GWAS Catalog, Nature genetics 2019, PMID:30578418. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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