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PLTP protein levels

near MMP9 · rs559072266

Where this position leads

Condition: Celiac Disease

rs559072266 Condition: Celiac Disease Celiac Disease Condition rs559072266 rs559072266 near MMP9

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.383 lower (95% confidence interval 0.26-0.51); p = 1 × 10−11.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 20, band 20q13.12 — between genes, 8.8 kb from MMP9.

What each result means

A/A No copy of the version the research linked to PLTP protein levels. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to PLTP protein levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to PLTP protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs559072266

What is rs559072266?

rs559072266 is a single position in the genome, in or near the near MMP9 gene. Published research associates it with pltp protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs559072266 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs559072266 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs559072266 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

PLTP protein levels (rs559072266). MyGeneLog™. https://www.mygenelog.com/variants/rs559072266

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