Sensitive

Coronary artery disease

SAYSD1 · rs55902013

Where this position leads

Condition: Coronary Artery Disease

rs55902013 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs55902013 rs55902013 SAYSD1

What the study found

Who was studied 15,302 Japanese ancestry cases, 76,014 European and East Asian ancestry cases, 36,140 Japanese ancestry controls, 264,785 European and East Asian ancestry controls.

The effect Each copy of the C allele carried 1.06 times the odds of Coronary artery disease (95% confidence interval 1.03-1.09); p = 4 × 10−10.

How common The C allele had a frequency of about 80% in the people studied.

Where it sits Chromosome 6, band 6p21.2 — between genes, 5.2 kb from KCNK5.

What each result means

C/C Two copies of the version the research linked to Coronary artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Coronary artery disease. That is a smaller link than two copies.
G/G No copy of the version the research linked to Coronary artery disease. This is the starting point the study compared everyone against.
Source

Questions about rs55902013

What is rs55902013?

rs55902013 is a single position in the genome, in or near the SAYSD1 gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs55902013 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs55902013 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55902013 come from?

GWAS Catalog, Circulation. Genomic and precision medicine 2020, PMID:32469254. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Coronary artery disease (rs55902013). MyGeneLog™. https://www.mygenelog.com/variants/rs55902013

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