Standard

Physical function (baseline)

CYBRD1 · rs55877758

What the study found

Who was studied 405,979 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0113 higher (95% confidence interval 0.0089-0.0137); p = 4 × 10−20.

How common The T allele had a frequency of about 76% in the people studied.

Where it sits Chromosome 2, band 2q31.1 — in an intron of CYBRD1.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Physical function (baseline) — no copies of the reported risk allele.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Physical function (baseline).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Physical function (baseline) compared to the general population.
Source

Questions about rs55877758

What is rs55877758?

rs55877758 is a single position in the genome, in or near the CYBRD1 gene. Published research associates it with physical function (baseline). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs55877758 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55877758 come from?

GWAS Catalog, Nature communications 2025, PMID:40374629. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Physical function (baseline) (rs55877758). MyGeneLog™. https://www.mygenelog.com/variants/rs55877758

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