Standard

Mean corpuscular haemoglobin (UKB data field 30050)

PSORS1C1 · rs558745444

Where this position leads

Condition: Celiac Disease

rs558745444 Condition: Celiac Disease Celiac Disease Condition rs558745444 rs558745444 PSORS1C1

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.109 higher (95% confidence interval 0.076-0.142); p = 1 × 10−11.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — in an intron of PSORS1C1.

What each result means

C/C No copy of the version the research linked to Mean corpuscular haemoglobin (UKB data field 30050). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Mean corpuscular haemoglobin (UKB data field 30050). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Mean corpuscular haemoglobin (UKB data field 30050). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs558745444

What is rs558745444?

rs558745444 is a single position in the genome, in or near the PSORS1C1 gene. Published research associates it with mean corpuscular haemoglobin (ukb data field 30050). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs558745444 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs558745444 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs558745444 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Mean corpuscular haemoglobin (UKB data field 30050) (rs558745444). MyGeneLog™. https://www.mygenelog.com/variants/rs558745444

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