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Fasting phospholipid levels in large HDL

OBSL1 · rs55873563

What the study found

The effect Each copy of the A allele shifted the measure 0.16 mmol/l higher (95% confidence interval 0.11-0.21); p = 4 × 10−9.

How common The A allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 2, band 2q35 — in an intron of OBSL1.

What ClinVar records

Classification Benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2021-06-19. ClinVar record 1286959 NM_015311.3(OBSL1):c.4066+36C>T

What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

A/A Two copies of the version the research linked to Fasting phospholipid levels in large HDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Fasting phospholipid levels in large HDL. That is a smaller link than two copies.
G/G No copy of the version the research linked to Fasting phospholipid levels in large HDL. This is the starting point the study compared everyone against.
Source

Questions about rs55873563

What is rs55873563?

rs55873563 is a single position in the genome, in or near the OBSL1 gene. Published research associates it with fasting phospholipid levels in large hdl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs55873563 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55873563 come from?

GWAS Catalog, Diabetes 2021, PMID:34610981. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Fasting phospholipid levels in large HDL (rs55873563). MyGeneLog™. https://www.mygenelog.com/variants/rs55873563

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