Sensitive

Mean platelet thrombocyte volume (UKB data field 30100)

near CCDC66 · rs558367900

Where this position leads

Condition: Celiac Disease

rs558367900 Condition: Celiac Disease Celiac Disease Condition rs558367900 rs558367900 near CCDC66

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.136 higher (95% confidence interval 0.095-0.176); p = 1 × 10−11.

How common The C allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 3, band 3p14.3 — between genes, 18.6 kb from CCDC66.

What each result means

C/C Two copies of the version the research linked to Mean platelet thrombocyte volume (UKB data field 30100). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Mean platelet thrombocyte volume (UKB data field 30100). That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean platelet thrombocyte volume (UKB data field 30100). This is the starting point the study compared everyone against.
Source

Questions about rs558367900

What is rs558367900?

rs558367900 is a single position in the genome, in or near the near CCDC66 gene. Published research associates it with mean platelet thrombocyte volume (ukb data field 30100). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs558367900 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs558367900 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs558367900 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Mean platelet thrombocyte volume (UKB data field 30100) (rs558367900). MyGeneLog™. https://www.mygenelog.com/variants/rs558367900

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