Standard
LDL cholesterol levels in current drinkers
CCDC93 · rs55809639
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals; replicated in 107,548 European ancestry individuals, 2,028 African American or Afro-Caribbean individuals, 41,240 Asian ancestry individuals, 6,622 Hispanic individuals, 1,984 Brazilian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 1.84 lower; p = 5 × 10−10.
Where it sits Chromosome 2, band 2q14.1 — between genes, 2.9 kb from INSIG2.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of LDL cholesterol levels in current drinkers compared to the general population.
A/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with LDL cholesterol levels in current drinkers.
T/T
Published research associates this genotype with typical/baseline likelihood of LDL cholesterol levels in current drinkers — no copies of the reported risk allele.
Source
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions
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and 254 more — show all
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American journal of epidemiology · 2019 · PMID 30698716
Questions about rs55809639
What is rs55809639?
rs55809639 is a single position in the genome, in or near the CCDC93 gene. Published research associates it with ldl cholesterol levels in current drinkers. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs55809639 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs55809639 come from?
GWAS Catalog, American journal of epidemiology 2019, PMID:30698716. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
LDL cholesterol levels in current drinkers (rs55809639). MyGeneLog™. https://www.mygenelog.com/variants/rs55809639
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