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Who was studied 12,086 European ancestry cases, 449,548 European ancestry controls; replicated in 31,307 cases, 211,753 controls, 3,164 East Asian ancestry cases, 20,134 East Asian ancestry controls.
The effect
Each copy of the A allele carried 1.06 times the odds of Peripheral artery disease (95% confidence interval 1.04-1.08); p = 1 × 10−10.
How common The A allele had a frequency of about 19% in the people studied.
Where it sits Chromosome 14, band 14q24.2 — between genes, 2.3 kb from SMOC1.
What each result means
A/ATwo copies of the version the research linked to Peripheral artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Peripheral artery disease. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Peripheral artery disease. This is the starting point the study compared everyone against.
Circulation. Genomic and precision medicine · 2021 · PMID 34601942 · open access
Questions about rs55784307
What is rs55784307?
rs55784307 is a single position in the genome, in or near the near SMOC1 gene. Published research associates it with peripheral artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs55784307 linked to?
On MyGeneLog this position is linked to Peripheral Artery Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs55784307 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs55784307 come from?
GWAS Catalog, Circulation. Genomic and precision medicine 2021, PMID:34601942. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 7214Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others4Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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