Standard

Insomnia

PPP1R10 · rs55777621

Where this position leads

Condition: Insomnia

rs55777621 Condition: Insomnia Insomnia Condition rs55777621 rs55777621 PPP1R10

What the study found

Who was studied 593,724 European ancestry cases, 1,771,286 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.019 higher (95% confidence interval 0.015-0.023); p = 2 × 10−14.

Where it sits Chromosome 6, band 6p21.33 — in an intron of PPP1R10.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Insomnia compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Insomnia.
G/G Published research associates this genotype with typical/baseline likelihood of Insomnia — no copies of the reported risk allele.
Source

Questions about rs55777621

What is rs55777621?

rs55777621 is a single position in the genome, in or near the PPP1R10 gene. Published research associates it with insomnia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs55777621 linked to?

On MyGeneLog this position is linked to Insomnia. The research behind each link, and its sources, are set out on that condition page.

Does having rs55777621 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55777621 come from?

GWAS Catalog, Nature genetics 2022, PMID:35835914. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Insomnia (rs55777621). MyGeneLog™. https://www.mygenelog.com/variants/rs55777621

← See all variants