Sensitive

Venous thromboembolism

MS4A4A · rs55777218

Where this position leads

Condition: Venous Thromboembolism

rs55777218 Condition: Venous Thromboembolism Venous Thromboembolism Condition rs55777218 rs55777218 MS4A4A

What the study found

Who was studied 7,177 European ancestry cases, 1,059,740 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0341 lower (95% confidence interval 0.022-0.046); p = 3 × 10−8.

How common The T allele had a frequency of about 64% in the people studied.

Where it sits Chromosome 11, band 11q12.2 — in an intron of MS4A4A.

What each result means

C/C No copy of the version the research linked to Venous thromboembolism. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Venous thromboembolism. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Venous thromboembolism. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs55777218

What is rs55777218?

rs55777218 is a single position in the genome, in or near the MS4A4A gene. Published research associates it with venous thromboembolism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs55777218 linked to?

On MyGeneLog this position is linked to Venous Thromboembolism. The research behind each link, and its sources, are set out on that condition page.

Does having rs55777218 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55777218 come from?

GWAS Catalog, Circulation 2022, PMID:36154123. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Venous thromboembolism (rs55777218). MyGeneLog™. https://www.mygenelog.com/variants/rs55777218

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