Standard

Cleft lip with cleft palate

CCDC26 · rs55768865

Where this position leads

Condition: Cleft Lip with Cleft Palate

rs55768865 Condition: Cleft Lip with Cleft Palate Cleft Lip with Cleft Palate Condition rs55768865 rs55768865 CCDC26

What the study found

Who was studied 725 Central and South American ancestry ancestry cases, 1,336 Central and South American ancestry ancestry controls, 328 European ancestry cases, 787 European ancestry controls, 157 Asian ancestry cases, 461 Asian ancestry controls, 96 African ancestry cases, 134 African ancestry controls.

The effect Each copy of the G allele shifted the measure 0.56 higher; p = 6 × 10−10.

Where it sits Chromosome 8, band 8q24.21 — in an intron of CCDC26.

What each result means

A/A No copy of the version the research linked to Cleft lip with cleft palate. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Cleft lip with cleft palate. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Cleft lip with cleft palate. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs55768865

What is rs55768865?

rs55768865 is a single position in the genome, in or near the CCDC26 gene. Published research associates it with cleft lip with cleft palate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs55768865 linked to?

On MyGeneLog this position is linked to Cleft Lip with Cleft Palate. The research behind each link, and its sources, are set out on that condition page.

Does having rs55768865 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55768865 come from?

GWAS Catalog, Genetic epidemiology 2022, PMID:35191549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cleft lip with cleft palate (rs55768865). MyGeneLog™. https://www.mygenelog.com/variants/rs55768865

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