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CLIC5 protein levels

CLIC5 · rs55766431

Where this position leads

Condition: Celiac Disease

rs55766431 Condition: Celiac Disease Celiac Disease Condition rs55766431 rs55766431 CLIC5

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0923 lower (95% confidence interval 0.065-0.12); p = 1 × 10−11.

How common The A allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 6, band 6p21.1 — inside CLIC5.

What each result means

A/A Two copies of the version the research linked to CLIC5 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to CLIC5 protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to CLIC5 protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs55766431

What is rs55766431?

rs55766431 is a single position in the genome, in or near the CLIC5 gene. Published research associates it with clic5 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs55766431 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs55766431 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55766431 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

CLIC5 protein levels (rs55766431). MyGeneLog™. https://www.mygenelog.com/variants/rs55766431

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