Standard
Glycated hemoglobin levels
ABCB11 · rs557462
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Glycated hemoglobin levels compared to the general population.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Glycated hemoglobin levels.
T/T
Published research associates this genotype with typical/baseline likelihood of Glycated hemoglobin levels — no copies of the reported risk allele.
Source
A Genome-Wide Association Study Identifies Blood Disorder-Related Variants Influencing Hemoglobin A<sub>1c</sub> With Implications for Glycemic Status in U.S. Hispanics/Latinos
Moon JY,
Louie TL,
Jain D,
Sofer T,
Schurmann C,
Below JE,
Lai CQ,
Aviles-Santa ML,
Talavera GA,
Smith CE,
Petty LE,
Bottinger EP
and 13 more — show all
Chen YI,
Taylor KD,
Daviglus ML,
Cai J,
Wang T,
Tucker KL,
Ordovás JM,
Hanis CL,
Loos RJF,
Schneiderman N,
Rotter JI,
Kaplan RC,
Qi Q
Diabetes care · 2019 · PMID 31213470
Questions about rs557462
What is rs557462?
rs557462 is a single position in the genome, in or near the ABCB11 gene. Published research associates it with glycated hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs557462 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs557462 come from?
GWAS Catalog, Diabetes Care 2019, PMID:31213470. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants