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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,669,029 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0102 lower (95% confidence interval 0.0084-0.012); p = 1 × 10−29.
How common The G allele had a frequency of about 36% in the people studied.
Where it sits Chromosome 1, band 1p35.1 — in an intron of PHC2.
What each result means
A/ANo copy of the version the research linked to Smoking initiation. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Smoking initiation. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Smoking initiation. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs55745410 is a single position in the genome, in or near the PHC2 gene. Published research associates it with smoking initiation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs55745410 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs55745410 come from?
GWAS Catalog, Nature 2022, PMID:36477530. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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