Sensitive

Chronic obstructive pulmonary disease liability (machine learning-based score)

TBX3-AS1 · rs55724378

What the study found

Who was studied 325,027 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0166 higher (95% confidence interval 0.012-0.021); p = 2 × 10−13.

Where it sits Chromosome 12, band 12q24.21 — in an intron of TBX3-AS1.

What each result means

A/A No copy of the version the research linked to Chronic obstructive pulmonary disease liability (machine learning-based score). This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Chronic obstructive pulmonary disease liability (machine learning-based score). That is a smaller link than two copies.
C/C Two copies of the version the research linked to Chronic obstructive pulmonary disease liability (machine learning-based score). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs55724378

What is rs55724378?

rs55724378 is a single position in the genome, in or near the TBX3-AS1 gene. Published research associates it with chronic obstructive pulmonary disease liability (machine learning-based score). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs55724378 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55724378 come from?

GWAS Catalog, Nature genetics 2023, PMID:37069358. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Chronic obstructive pulmonary disease liability (machine learning-based score) (rs55724378). MyGeneLog™. https://www.mygenelog.com/variants/rs55724378

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