Standard

HDL cholesterol

RP11-69G7.1 · rs55703462

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs55703462 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs55703462 rs55703462 RP11-69G7.1

What the study found

Who was studied 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals; replicated in Up to 319,677 individuals.

The effect Each copy of the A allele shifted the measure 0.0187 mg dl-1 lower (95% confidence interval 0.013-0.025); p = 3 × 10−9.

How common The A allele had a frequency of about 50% in the people studied.

Where it sits Chromosome 15, band 15q22.2 — between genes, 18.6 kb from LACTB.

What each result means

A/A Two copies of the version the research linked to HDL cholesterol. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to HDL cholesterol. That is a smaller link than two copies.
G/G No copy of the version the research linked to HDL cholesterol. This is the starting point the study compared everyone against.
Source

Questions about rs55703462

What is rs55703462?

rs55703462 is a single position in the genome, in or near the RP11-69G7.1 gene. Published research associates it with hdl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs55703462 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs55703462 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55703462 come from?

GWAS Catalog, Nature genetics 2018, PMID:30275531. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

HDL cholesterol (rs55703462). MyGeneLog™. https://www.mygenelog.com/variants/rs55703462

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