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Serum 25-Hydroxyvitamin D level variance

CALCB · rs55683806

What the study found

Who was studied 318,851 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0374 lower (95% confidence interval -0.048--0.026); p = 2 × 10−11.

How common The A allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 11, band 11p15.2 — inside CALCB.

What each result means

A/A Two copies of the version the research linked to Serum 25-Hydroxyvitamin D level variance. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Serum 25-Hydroxyvitamin D level variance. That is a smaller link than two copies.
T/T No copy of the version the research linked to Serum 25-Hydroxyvitamin D level variance. This is the starting point the study compared everyone against.
Source

Questions about rs55683806

What is rs55683806?

rs55683806 is a single position in the genome, in or near the CALCB gene. Published research associates it with serum 25-hydroxyvitamin d level variance. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs55683806 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55683806 come from?

GWAS Catalog, Nature communications 2020, PMID:32242144. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Serum 25-Hydroxyvitamin D level variance (rs55683806). MyGeneLog™. https://www.mygenelog.com/variants/rs55683806

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