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Cerebrospinal fluid AB1-42 levels

RNU3P2 · rs55644114

What the study found

Who was studied 305 European ancestry cognitively normal individuals, 581 European ancestry mild cognitive impairment cases, 190 European ancestry Alzheimer's disease dementia cases.

The effect Each copy of the A allele shifted the measure 0.41 higher (95% confidence interval 0.27-0.55); p = 3 × 10−8.

How common The A allele had a frequency of about 16% in the people studied.

Where it sits Chromosome 8, band 8p21.3 — in a regulatory region of LOC105379315.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cerebrospinal fluid AB1-42 levels compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cerebrospinal fluid AB1-42 levels.
G/G Published research associates this genotype with typical/baseline likelihood of Cerebrospinal fluid AB1-42 levels — no copies of the reported risk allele.
Source

Questions about rs55644114

What is rs55644114?

rs55644114 is a single position in the genome, in or near the RNU3P2 gene. Published research associates it with cerebrospinal fluid ab1-42 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs55644114 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55644114 come from?

GWAS Catalog, Alzheimers Dement 2017, PMID:29274321. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cerebrospinal fluid AB1-42 levels (rs55644114). MyGeneLog™. https://www.mygenelog.com/variants/rs55644114

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