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Who was studied 986 European ancestry cases, 4,946 European ancestry controls; replicated in 4,009 cases, 4,066 controls.
The effect
Each copy of the G allele carried 1.17 times the odds of Testicular germ cell tumor (95% confidence interval 1.09-1.24); p = 3 × 10−9.
How common The G allele had a frequency of about 37% in the people studied.
Where it sits Chromosome 16, band 16q24.2 — in an intron of ZFPM1.
What each result means
C/CNo copy of the version the research linked to Testicular germ cell tumor. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Testicular germ cell tumor. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Testicular germ cell tumor. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2015 · PMID 26503584 · open access
Questions about rs55637647
What is rs55637647?
rs55637647 is a single position in the genome, in or near the ZFPM1 gene. Published research associates it with testicular germ cell tumor. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs55637647 linked to?
On MyGeneLog this position is linked to Testicular Germ Cell Tumour. The research behind each link, and its sources, are set out on that condition page.
Does having rs55637647 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs55637647 come from?
GWAS Catalog, Nat Commun 2015, PMID:26503584. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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