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Age-related hearing impairment

TUB · rs55635402

What the study found

Who was studied 121,934 European ancestry cases, 591,699 European ancestry controls.

The effect Each copy of the G allele carried 0.96 times the odds of Age-related hearing impairment; p = 4 × 10−12.

Where it sits Chromosome 11, band 11p15.4 — in a non-coding transcript of TUB.

What each result means

A/A No copy of the version the research linked to Age-related hearing impairment. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Age-related hearing impairment. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Age-related hearing impairment. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs55635402

What is rs55635402?

rs55635402 is a single position in the genome, in or near the TUB gene. Published research associates it with age-related hearing impairment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs55635402 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs55635402 come from?

GWAS Catalog, Communications biology 2021, PMID:34108613. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Age-related hearing impairment (rs55635402). MyGeneLog™. https://www.mygenelog.com/variants/rs55635402

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