KDM4C · rs554596237
Where this position leads
Condition: Tuberculosis
What the study found
Who was studied 12 Vis (founder/genetic isolate) cases, 16 Korculan (founder/genetic isolate) cases, 6 Split cases, 948 Vis (founder/genetic isolate) controls, 2,682 Korculan (founder/genetic isolate) controls, 960 Split controls.
The effect Each copy of the G allele carried 1.09 times the odds of Tuberculosis (95% confidence interval 1.07-1.12); p = 2 × 10−11.
How common The G allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 9, band 9p24.1 — in an intron of KDM4C.
rs554596237 is a single position in the genome, in or near the KDM4C gene. Published research associates it with tuberculosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Tuberculosis. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, International journal of molecular sciences 2023, PMID:37108169. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Tuberculosis (rs554596237). MyGeneLog™. https://www.mygenelog.com/variants/rs554596237