Sensitive

Biological Grandparent (maternal): Bipolar Disorder

DDX25 · rs552029205

Where this position leads

Condition: Bipolar Disorder

rs552029205 Condition: Bipolar Disorder Bipolar Disorder Condition rs552029205 rs552029205 DDX25

What the study found

Who was studied 287 African American or Afro-Caribbean cases, 55,218 African American or Afro-Caribbean controls, 1,621 European ancestry cases, 314,047 European ancestry controls.

The effect Each copy of the G allele shifted the measure 3.27 lower (95% confidence interval 3.24-3.29); p = 4 × 10−11.

How common The G allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 11, band 11q24.2 — inside DDX25.

What each result means

A/A No copy of the version the research linked to Biological Grandparent (maternal): Bipolar Disorder. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Biological Grandparent (maternal): Bipolar Disorder. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Biological Grandparent (maternal): Bipolar Disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs552029205

What is rs552029205?

rs552029205 is a single position in the genome, in or near the DDX25 gene. Published research associates it with biological grandparent (maternal): bipolar disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs552029205 linked to?

On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs552029205 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs552029205 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Biological Grandparent (maternal): Bipolar Disorder (rs552029205). MyGeneLog™. https://www.mygenelog.com/variants/rs552029205

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