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Who was studied 16,595 European ancestry cases, 523,330 European ancestry controls.
The effect
Each copy of the T allele carried 2.71 times the odds of Uterine fibroids (95% confidence interval 2.05-3.57); p = 4 × 10−12.
How common The T allele had a frequency of about 0% in the people studied.
Where it sits Chromosome 4, band 4p11 — in an intron of SLAIN2.
What each result means
C/CNo copy of the version the research linked to Uterine fibroids. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Uterine fibroids. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Uterine fibroids. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2018 · PMID 30194396 · open access
Questions about rs551980034
What is rs551980034?
rs551980034 is a single position in the genome, in or near the SLAIN2 gene. Published research associates it with uterine fibroids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs551980034 linked to?
On MyGeneLog this position is linked to Uterine Fibroids. The research behind each link, and its sources, are set out on that condition page.
Does having rs551980034 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs551980034 come from?
GWAS Catalog, Nature communications 2018, PMID:30194396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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