Optic nerve head parameters (multi-trait analysis)
ZAK · rs551947583
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied up to 25,180 European ancestry individuals; replicated in up to 7,792 Chinese ancestry individuals, 3,280 Malay ancestry individuals, 3,400 Indian ancestry individuals.
The effect
The reported allele is T; the catalogue records no effect size
; p = 9 × 10−10.
How common The T allele had a frequency of about 0% in the people studied.
Where it sits Chromosome 2, band 2q31.1 — in an intron of MAP3K20-AS1.
What each result means
C/CNo copy of the version the research linked to Optic nerve head parameters (multi-trait analysis). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Optic nerve head parameters (multi-trait analysis). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Optic nerve head parameters (multi-trait analysis). That is the strongest link of the three results. A link in a study is not a diagnosis.
Communications biology · 2019 · PMID 31798171 · open access
Questions about rs551947583
What is rs551947583?
rs551947583 is a single position in the genome, in or near the ZAK gene. Published research associates it with optic nerve head parameters (multi-trait analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs551947583 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs551947583 come from?
GWAS Catalog, Communications biology 2019, PMID:31798171. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Optic nerve head parameters (multi-trait analysis) (rs551947583). MyGeneLog™. https://www.mygenelog.com/variants/rs551947583