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Who was studied 211 African American or Afro-Caribbean cases, 121,601 African American or Afro-Caribbean controls, 540 European ancestry cases, 450,490 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 3.4 lower (95% confidence interval 3.38-3.42); p = 9 × 10−13.
How common The G allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 10, band 10q22.3 — in an intron of ZCCHC24.
What each result means
A/ANo copy of the version the research linked to Neuroendocrine tumors (PheCode 209). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Neuroendocrine tumors (PheCode 209). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Neuroendocrine tumors (PheCode 209). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs551907375
What is rs551907375?
rs551907375 is a single position in the genome, in or near the ZCCHC24 gene. Published research associates it with neuroendocrine tumors (phecode 209). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs551907375 linked to?
On MyGeneLog this position is linked to Neuroendocrine Tumors. The research behind each link, and its sources, are set out on that condition page.
Does having rs551907375 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs551907375 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1714822Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot8Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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