Standard

Cirrhosis

HDAC9 · rs551625260

Where this position leads

Condition: Alcohol-Related Cirrhosis

rs551625260 Condition: Alcohol-Related Cirrhosis Alcohol-Related Cirrhosis Condition rs551625260 rs551625260 HDAC9

What the study found

Who was studied 122 European ancestry cases, 347,284 European ancestry controls, 2,551 East Asian ancestry cases, 176,175 East Asian ancestry controls.

The effect Each copy of the A allele shifted the measure 4.62 higher (95% confidence interval 2.98-6.25); p = 3 × 10−8.

Where it sits Chromosome 7, band 7p21.1 — in an intron of HDAC9.

What each result means

A/A Two copies of the version the research linked to Cirrhosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Cirrhosis. That is a smaller link than two copies.
T/T No copy of the version the research linked to Cirrhosis. This is the starting point the study compared everyone against.
Source

Questions about rs551625260

What is rs551625260?

rs551625260 is a single position in the genome, in or near the HDAC9 gene. Published research associates it with cirrhosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs551625260 linked to?

On MyGeneLog this position is linked to Alcohol-Related Cirrhosis. The research behind each link, and its sources, are set out on that condition page.

Does having rs551625260 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs551625260 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cirrhosis (rs551625260). MyGeneLog™. https://www.mygenelog.com/variants/rs551625260

← See all variants