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CDH17 protein levels

near RPL34P18 · rs551073421

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.178 higher (95% confidence interval 0.14-0.22); p = 3 × 10−20.

How common The C allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 8, band 8q22.1 — between genes, 37.6 kb from RPL34P18.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of CDH17 protein levels compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with CDH17 protein levels.
T/T Published research associates this genotype with typical/baseline likelihood of CDH17 protein levels — no copies of the reported risk allele.
Source

Questions about rs551073421

What is rs551073421?

rs551073421 is a single position in the genome, in or near the near RPL34P18 gene. Published research associates it with cdh17 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs551073421 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs551073421 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

CDH17 protein levels (rs551073421). MyGeneLog™. https://www.mygenelog.com/variants/rs551073421

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