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Atrial fibrillation/atrial flutter

KIF1B · rs551033057

Where this position leads

Condition: Atrial Fibrillation

rs551033057 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs551033057 rs551033057 KIF1B

What the study found

Who was studied 29,212 European ancestry cases, 400,539 European ancestry controls, 4,150 East Asian ancestry cases, 155,540 East Asian ancestry controls.

The effect Each copy of the G allele shifted the measure 0.668 higher (95% confidence interval 0.47-0.86); p = 2 × 10−11.

Where it sits Chromosome 1, band 1p36.22 — in an intron of KIF1B.

What each result means

A/A No copy of the version the research linked to Atrial fibrillation/atrial flutter. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Atrial fibrillation/atrial flutter. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Atrial fibrillation/atrial flutter. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs551033057

What is rs551033057?

rs551033057 is a single position in the genome, in or near the KIF1B gene. Published research associates it with atrial fibrillation/atrial flutter. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs551033057 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs551033057 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs551033057 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atrial fibrillation/atrial flutter (rs551033057). MyGeneLog™. https://www.mygenelog.com/variants/rs551033057

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