Standard

Homocysteine levels

SLC17A3 · rs548987

Where this position leads

Condition: Homocysteine Levels

rs548987 Condition: Homocysteine Levels Homocysteine Levels Condition rs548987 rs548987 SLC17A3

What the study found

Who was studied 44,147 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0597 higher (95% confidence interval 0.04-0.079); p = 1 × 10−8.

How common The C allele had a frequency of about 13% in the people studied.

Where it sits Chromosome 6, band 6p22.2 — in an intron of SLC17A3.

What each result means

C/C Two copies of the version the research linked to Homocysteine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Homocysteine levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Homocysteine levels. This is the starting point the study compared everyone against.
Source

Questions about rs548987

What is rs548987?

rs548987 is a single position in the genome, in or near the SLC17A3 gene. Published research associates it with homocysteine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs548987 linked to?

On MyGeneLog this position is linked to Homocysteine Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs548987 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs548987 come from?

GWAS Catalog, Am J Clin Nutr 2013, PMID:23824729. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Homocysteine levels (rs548987). MyGeneLog™. https://www.mygenelog.com/variants/rs548987

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