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Lifespan

CELF2 · rs547541271

Where this position leads

Condition: Human Lifespan and Longevity

rs547541271 Condition: Human Lifespan and Longevity Human Lifespan and Longevity Condition rs547541271 rs547541271 CELF2

What the study found

Who was studied 212,863 British ancestry females.

The effect Each copy of the T allele shifted the measure 0.04 higher; p = 3 × 10−8.

Where it sits Chromosome 10, band 10p14 — in an intron of CELF2.

What each result means

C/C No copy of the version the research linked to Lifespan. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Lifespan. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Lifespan. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs547541271

What is rs547541271?

rs547541271 is a single position in the genome, in or near the CELF2 gene. Published research associates it with lifespan. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs547541271 linked to?

On MyGeneLog this position is linked to Human Lifespan and Longevity. The research behind each link, and its sources, are set out on that condition page.

Does having rs547541271 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs547541271 come from?

GWAS Catalog, Nature communications 2025, PMID:40021682. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lifespan (rs547541271). MyGeneLog™. https://www.mygenelog.com/variants/rs547541271

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