Sensitive

Alzheimer's disease or family history of Alzheimer's disease

BCAM · rs547509922

Where this position leads

Condition: Alzheimer's Disease

rs547509922 Condition: Alzheimer's Disease Alzheimer's Disease Condition rs547509922 rs547509922 BCAM

What the study found

Who was studied 24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls.

The effect Each copy of the T allele shifted the measure 7.31 z-unit higher; p = 3 × 10−13.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 19, band 19q13.32 — between genes, 6.6 kb from BCAM.

What each result means

C/C No copy of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs547509922

What is rs547509922?

rs547509922 is a single position in the genome, in or near the BCAM gene. Published research associates it with alzheimer's disease or family history of alzheimer's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs547509922 linked to?

On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs547509922 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs547509922 come from?

GWAS Catalog, Nat Genet 2019, PMID:30617256. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Alzheimer's disease or family history of Alzheimer's disease (rs547509922). MyGeneLog™. https://www.mygenelog.com/variants/rs547509922

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