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Morning person

DHODH · rs5467

What the study found

Who was studied 252,287 European ancestry cases, 150,908 European ancestry controls; replicated in 120,478 European ancestry cases, 127,622 European ancestry controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 2 × 10−15.

How common The C allele had a frequency of about 79% in the people studied.

Where it sits Chromosome 16, band 16q22.2 — between genes, 0.1 kb from HP.

What each result means

C/C Two copies of the version the research linked to Morning person. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Morning person. That is a smaller link than two copies.
T/T No copy of the version the research linked to Morning person. This is the starting point the study compared everyone against.
Source

Questions about rs5467

What is rs5467?

rs5467 is a single position in the genome, in or near the DHODH gene. Published research associates it with morning person. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs5467 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs5467 come from?

GWAS Catalog, Nature communications 2019, PMID:30696823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Morning person (rs5467). MyGeneLog™. https://www.mygenelog.com/variants/rs5467

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