0 71222Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others2Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 53,711 European ancestry female cases, 380,441 European ancestry female controls, 14,905 East Asian ancestry female cases, 69,609 East Asian ancestry female controls, 14,905 Central Asian ancestry female cases, 69,609 Central Asian ancestry female controls, 14,905 South Asian ancestry female cases, 69,609 South Asian ancestry female controls, 5,678 African ancestry female cases, 15,760 African ancestry female controls.
The effect
Each copy of the T allele shifted the measure 0.25 higher (95% confidence interval 0.18-0.32); p = 3 × 10−13.
Where it sits Chromosome 10, band 10q25.1 — in an intron of CFAP58.
What each result means
C/CNo copy of the version the research linked to Uterine fibroids. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Uterine fibroids. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Uterine fibroids. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2025 · PMID 40050615 · open access
Questions about rs544934450
What is rs544934450?
rs544934450 is a single position in the genome, in or near the CFAP58 gene. Published research associates it with uterine fibroids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs544934450 linked to?
On MyGeneLog this position is linked to Uterine Fibroids. The research behind each link, and its sources, are set out on that condition page.
Does having rs544934450 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs544934450 come from?
GWAS Catalog, Nature communications 2025, PMID:40050615. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 71222Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others2Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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