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Thyroid peroxidase antibody positive in pregnancy

near ZSCAN16-AS1 · rs544856801

What the study found

Who was studied 10,163 Chinese ancestry cases, 58,683 Chinese ancestry controls; replicated in 40,018 Chinese ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.646 higher (95% confidence interval 0.49-0.8); p = 9 × 10−16.

How common The T allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 6, band 6p22.1 — between genes, 13.9 kb from ZSCAN16-AS1.

What each result means

A/A No copy of the version the research linked to Thyroid peroxidase antibody positive in pregnancy. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Thyroid peroxidase antibody positive in pregnancy. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Thyroid peroxidase antibody positive in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs544856801

What is rs544856801?

rs544856801 is a single position in the genome, in or near the near ZSCAN16-AS1 gene. Published research associates it with thyroid peroxidase antibody positive in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs544856801 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs544856801 come from?

GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Thyroid peroxidase antibody positive in pregnancy (rs544856801). MyGeneLog™. https://www.mygenelog.com/variants/rs544856801

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