Standard

Gout (PheCode 274.1)

near FLJ46284 · rs544648171

Where this position leads

Condition: Gout

rs544648171 Condition: Gout Gout Condition rs544648171 rs544648171 near FLJ46284

What the study found

Who was studied 375 European ancestry cases, 455,973 European ancestry controls.

The effect Each copy of the T allele shifted the measure 5.54 higher (95% confidence interval 3.7-7.38); p = 4 × 10−9.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 8, band 8q22.1 — between genes, 147.5 kb from FLJ46284.

What each result means

A/A No copy of the version the research linked to Gout (PheCode 274.1). This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Gout (PheCode 274.1). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Gout (PheCode 274.1). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs544648171

What is rs544648171?

rs544648171 is a single position in the genome, in or near the near FLJ46284 gene. Published research associates it with gout (phecode 274.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs544648171 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs544648171 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs544648171 come from?

GWAS Catalog, Nature genetics 2021, PMID:34737426. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Gout (PheCode 274.1) (rs544648171). MyGeneLog™. https://www.mygenelog.com/variants/rs544648171

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