Standard

Free cholesterol to total lipids ratio in chylomicrons and extremely large VLDL

SLC22A3 · rs544366796

What the study found

Who was studied 111,638 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.299 lower (95% confidence interval 0.26-0.34); p = 3 × 10−47.

How common The C allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 6, band 6q25.3 — in an intron of SLC22A3.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Free cholesterol to total lipids ratio in chylomicrons and extremely large VLDL compared to the general population.
C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Free cholesterol to total lipids ratio in chylomicrons and extremely large VLDL.
G/G Published research associates this genotype with typical/baseline likelihood of Free cholesterol to total lipids ratio in chylomicrons and extremely large VLDL — no copies of the reported risk allele.
Source

Questions about rs544366796

What is rs544366796?

rs544366796 is a single position in the genome, in or near the SLC22A3 gene. Published research associates it with free cholesterol to total lipids ratio in chylomicrons and extremely large vldl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs544366796 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs544366796 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Free cholesterol to total lipids ratio in chylomicrons and extremely large VLDL (rs544366796). MyGeneLog™. https://www.mygenelog.com/variants/rs544366796

← See all variants