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Hirsutism

near ANTXR2 · rs544265360

Where this position leads

Condition: Hirsutism

rs544265360 Condition: Hirsutism Hirsutism Condition rs544265360 rs544265360 near ANTXR2

What the study found

Who was studied 1,004 European ancestry female cases, 345,552 European ancestry female controls, 3,830 East Asian ancestry female cases, 7,414 East Asian ancestry female controls.

The effect Each copy of the A allele carried 4.92 times the odds of Hirsutism (95% confidence interval 3.04-7.97); p = 9 × 10−11.

How common The A allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 4, band 4q21.21 — between genes, 46.3 kb from PCAT4.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hirsutism compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hirsutism.
G/G Published research associates this genotype with typical/baseline likelihood of Hirsutism — no copies of the reported risk allele.
Source
Hirsutism beyond PCOS: Genome-wide evidence for genetic factors
Takala JH, Pujol-Gualdo N, Laisk T, Uimari O, Piltonen T, Kettunen J, Tyrmi JS
FinnGen · Estonian Biobank Research Team
The Journal of investigative dermatology · 2026 · PMID 42190866

Questions about rs544265360

What is rs544265360?

rs544265360 is a single position in the genome, in or near the near ANTXR2 gene. Published research associates it with hirsutism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs544265360 linked to?

On MyGeneLog this position is linked to Hirsutism. The research behind each link, and its sources, are set out on that condition page.

Does having rs544265360 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs544265360 come from?

GWAS Catalog, The Journal of investigative dermatology 2026, PMID:42190866. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hirsutism (rs544265360). MyGeneLog™. https://www.mygenelog.com/variants/rs544265360

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