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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 157,662 European ancestry individuals; replicated in 26,154 European, Central Asian and unknown ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0757 higher (95% confidence interval 0.057-0.094); p = 1 × 10−15.
How common The C allele had a frequency of about 4% in the people studied.
Where it sits Chromosome 22, band 22q13.2 — between genes, 11.7 kb from Y_RNA.
What each result means
C/CTwo copies of the version the research linked to Grapefruit liking. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Grapefruit liking. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Grapefruit liking. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 35585065 · open access
Questions about rs543760429
What is rs543760429?
rs543760429 is a single position in the genome, in or near the near Y_RNA gene. Published research associates it with grapefruit liking. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs543760429 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs543760429 come from?
GWAS Catalog, Nature communications 2022, PMID:35585065. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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