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GLIPR1 protein levels

near Y_RNA · rs542495534

Where this position leads

Condition: Celiac Disease

rs542495534 Condition: Celiac Disease Celiac Disease Condition rs542495534 rs542495534 near Y_RNA

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.596 lower (95% confidence interval 0.42-0.77); p = 1 × 10−11.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 1, band 1q43 — between genes, 29.2 kb from Y_RNA.

What each result means

A/A No copy of the version the research linked to GLIPR1 protein levels. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to GLIPR1 protein levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to GLIPR1 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs542495534

What is rs542495534?

rs542495534 is a single position in the genome, in or near the near Y_RNA gene. Published research associates it with glipr1 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs542495534 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs542495534 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs542495534 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

GLIPR1 protein levels (rs542495534). MyGeneLog™. https://www.mygenelog.com/variants/rs542495534

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