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ICAM2 protein levels

DCBLD2 · rs541615798

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.21 higher (95% confidence interval 0.15-0.27); p = 4 × 10−15.

How common The A allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 3, band 3q12.1 — in an intron of DCBLD2.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of ICAM2 protein levels compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with ICAM2 protein levels.
G/G Published research associates this genotype with typical/baseline likelihood of ICAM2 protein levels — no copies of the reported risk allele.
Source

Questions about rs541615798

What is rs541615798?

rs541615798 is a single position in the genome, in or near the DCBLD2 gene. Published research associates it with icam2 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs541615798 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs541615798 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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ICAM2 protein levels (rs541615798). MyGeneLog™. https://www.mygenelog.com/variants/rs541615798

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