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Daytime nap

ZNF385D · rs541594711

Where this position leads

What the study found

Who was studied 113,054 European ancestry cases and controls.

The effect Each copy of the A allele shifted the measure 0.3 higher (95% confidence interval 0.2-0.4); p = 2 × 10⁻⁸.

How common The A allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 3, band 3p24.3 — in an intron of ZNF385D.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Daytime nap compared to the general population.

A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Daytime nap.

C/C Published research associates this genotype with typical/baseline likelihood of Daytime nap — no copies of the reported risk allele.

Source

Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits

Hammerschlag AR, Stringer S, de Leeuw CA, Sniekers S, Taskesen E, Watanabe K, Blanken TF, Dekker K, Te Lindert BHW, Wassing R, Jonsdottir I, Thorleifsson G

and 10 more — show all

Stefansson H, Gislason T, Berger K, Schormair B, Wellmann J, Winkelmann J, Stefansson K, Oexle K, Van Someren EJW, Posthuma D

Nature genetics · 2017 · PMID 28604731 · open access

Questions about rs541594711

What is rs541594711?

rs541594711 is a single position in the genome, in or near the ZNF385D gene. Published research associates it with daytime nap. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs541594711 linked to?

On MyGeneLog this position is linked to Sleep and Circadian Rhythm. The research behind each link, and its sources, are set out on that condition page.

Does having rs541594711 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs541594711 come from?

GWAS Catalog, Nat Genet 2017, PMID:28604731. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Daytime nap (rs541594711). MyGeneLog™. https://www.mygenelog.com/variants/rs541594711

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