Sex hormone-binding globulin levels adjusted for BMI
near RNU6-543P · rs541030121
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 368,929 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0163 higher (95% confidence interval 0.012-0.021); p = 6 × 10−15.
How common The A allele had a frequency of about 6% in the people studied.
Where it sits Chromosome 10, band 10q21.3 — between genes, 1.9 kb from RNU6-543P.
What each result means
A/ATwo copies of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. This is the starting point the study compared everyone against.
Nature medicine · 2020 · PMID 32042192 · open access
Questions about rs541030121
What is rs541030121?
rs541030121 is a single position in the genome, in or near the near RNU6-543P gene. Published research associates it with sex hormone-binding globulin levels adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs541030121 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs541030121 come from?
GWAS Catalog, Nature medicine 2020, PMID:32042192. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Sex hormone-binding globulin levels adjusted for BMI (rs541030121). MyGeneLog™. https://www.mygenelog.com/variants/rs541030121