Estimated glomerular filtration rate in sickle cell disease
RAB11A · rs540404388
1 1028Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others8Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 966 individuals.
The effect
Each copy of the C allele shifted the measure 26.4 higher (95% confidence interval 17.05-35.81); p = 3 × 10−8.
Where it sits Chromosome 15, band 15q22.31 — inside RAB11A.
What each result means
C/CTwo copies of the version the research linked to Estimated glomerular filtration rate in sickle cell disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Estimated glomerular filtration rate in sickle cell disease. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Estimated glomerular filtration rate in sickle cell disease. This is the starting point the study compared everyone against.
rs540404388 is a single position in the genome, in or near the RAB11A gene. Published research associates it with estimated glomerular filtration rate in sickle cell disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs540404388 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs540404388 come from?
GWAS Catalog, Blood advances 2026, PMID:42616615. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 1028Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others8Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.