Standard

Waist circumference adjusted for body mass index

ADAM28 · rs540309444

Where this position leads

Condition: Waist Circumference

rs540309444 Condition: Waist Circumference Waist Circumference Condition rs540309444 rs540309444 ADAM28

What the study found

Who was studied 186,825 British ancestry men.

The effect Each copy of the G allele shifted the measure 0.0259 lower (95% confidence interval 0.019-0.033); p = 6 × 10−13.

Where it sits Chromosome 8, band 8p21.2 — in an intron of ADAM7-AS1.

What each result means

A/A No copy of the version the research linked to Waist circumference adjusted for body mass index. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Waist circumference adjusted for body mass index. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Waist circumference adjusted for body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs540309444

What is rs540309444?

rs540309444 is a single position in the genome, in or near the ADAM28 gene. Published research associates it with waist circumference adjusted for body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs540309444 linked to?

On MyGeneLog this position is linked to Waist Circumference. The research behind each link, and its sources, are set out on that condition page.

Does having rs540309444 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs540309444 come from?

GWAS Catalog, Scientific reports 2021, PMID:34021172. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Waist circumference adjusted for body mass index (rs540309444). MyGeneLog™. https://www.mygenelog.com/variants/rs540309444

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