0 302211722319Reads by AI crawlersClaude2ChatGPT2Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total30Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 500,123 European ancestry individuals,16,962 East Asian, South Asian, Hispanic and African American ancestry individuals.
The effect
The reported allele is T; the catalogue records no effect size
; p = 1 × 10−14.
How common The T allele had a frequency of about 48% in the people studied.
Where it sits Chromosome 6, band 6q25.3 — in an intron of SLC22A3.
What each result means
C/CNo copy of the version the research linked to Body mass index and triglycerides (pairwise). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Body mass index and triglycerides (pairwise). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Body mass index and triglycerides (pairwise). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs539958 is a single position in the genome, in or near the SLC22A3 gene. Published research associates it with body mass index and triglycerides (pairwise). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs539958 linked to?
On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.
Does having rs539958 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs539958 come from?
GWAS Catalog, Nat Metab 2021, PMID:33619380. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 302211722319Reads by AI crawlersClaude2ChatGPT2Google · Gemini1Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total30Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Body mass index and triglycerides (pairwise) (rs539958). MyGeneLog™. https://www.mygenelog.com/variants/rs539958