Standard
Body mass index and triglycerides (pairwise)
SLC22A3 · rs539958
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Body mass index and triglycerides (pairwise) — no copies of the reported risk allele. (GWAS Catalog, Nat Metab 2021, PMID:33619380)
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Body mass index and triglycerides (pairwise). (GWAS Catalog, Nat Metab 2021, PMID:33619380)
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Body mass index and triglycerides (pairwise) compared to the general population. (GWAS Catalog, Nat Metab 2021, PMID:33619380)
Source
Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities
Huang LO,
Rauch A,
Mazzaferro E,
Preuss M,
Carobbio S,
Bayrak CS,
Chami N,
Wang Z,
Schick UM,
Yang N,
Itan Y,
Vidal-Puig A
and 4 more — show all
Nature metabolism · 2021 · PMID 33619380
Questions about rs539958
What is rs539958?
rs539958 is a single position in the genome, in or near the SLC22A3 gene. Published research associates it with body mass index and triglycerides (pairwise). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs539958 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs539958 come from?
GWAS Catalog, Nat Metab 2021, PMID:33619380. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants