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Albuminuria

CUBN · rs539606836

What the study found

Who was studied 217,634 European ancestry individuals; replicated in 108,800 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 1.94 higher (95% confidence interval 1.43-2.45); p = 1 × 10−13.

How common The A allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 10, band 10p13 — in an intron of CUBN.

What each result means

A/A Two copies of the version the research linked to Albuminuria. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Albuminuria. That is a smaller link than two copies.
G/G No copy of the version the research linked to Albuminuria. This is the starting point the study compared everyone against.
Source

Questions about rs539606836

What is rs539606836?

rs539606836 is a single position in the genome, in or near the CUBN gene. Published research associates it with albuminuria. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs539606836 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs539606836 come from?

GWAS Catalog, Kidney international 2019, PMID:30910378. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Albuminuria (rs539606836). MyGeneLog™. https://www.mygenelog.com/variants/rs539606836

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