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Atopic dermatitis

PGLYRP4 · rs538763482

Where this position leads

Condition: Atopic Dermatitis

rs538763482 Condition: Atopic Dermatitis Atopic Dermatitis Condition rs538763482 rs538763482 PGLYRP4

What the study found

Who was studied 35,156 European ancestry cases, 846,868 European ancestry controls, 2,385 Japanese ancestry cases, 209,651 Japanese ancestry controls.

The effect Each copy of the A allele shifted the measure 0.513 lower (95% confidence interval 0.4-0.63); p = 2 × 10−18.

Where it sits Chromosome 1, band 1q21.3 — in the 3′ untranslated region of PGLYRP4.

What each result means

A/A Two copies of the version the research linked to Atopic dermatitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Atopic dermatitis. That is a smaller link than two copies.
G/G No copy of the version the research linked to Atopic dermatitis. This is the starting point the study compared everyone against.
Source

Questions about rs538763482

What is rs538763482?

rs538763482 is a single position in the genome, in or near the PGLYRP4 gene. Published research associates it with atopic dermatitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs538763482 linked to?

On MyGeneLog this position is linked to Atopic Dermatitis. The research behind each link, and its sources, are set out on that condition page.

Does having rs538763482 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs538763482 come from?

GWAS Catalog, The Journal of investigative dermatology 2024, PMID:38663478. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Atopic dermatitis (rs538763482). MyGeneLog™. https://www.mygenelog.com/variants/rs538763482

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